{"id":4146,"date":"2026-06-30T16:31:25","date_gmt":"2026-06-30T16:31:25","guid":{"rendered":"https:\/\/aestx-systems.com\/?post_type=product&p=4146"},"modified":"2026-07-23T09:32:39","modified_gmt":"2026-07-23T09:32:39","slug":"ahk-cu","status":"publish","type":"product","link":"https:\/\/aestx-systems.com\/en\/product\/ahk-cu\/","title":{"rendered":"AHK-Cu"},"content":{"rendered":"

AHK-Cu (copper tripeptide-3)<\/strong> is a synthetic tripeptide with the sequence alanyl-L-histidyl-L-lysine, which complexes a copper ion (Cu\u00b2\u207a) with high affinity. AHK-Cu is closely related to naturally occurring GHK-Cu and differs structurally only by replacing glycine with alanine at the first position. This small change shifts its research profile towards hair follicle biology and makes AHK-Cu one of the most targeted copper peptides in follicular research.<\/p>\n

Research areas for AHK-Cu (copper tripeptide-3)<\/h2>\n

Hair follicle & anagen research<\/h3>\n

The scientific focus of AHK-Cu is the biology of dermal papilla cells, the control centres at the base of each hair follicle. In vitro models investigate how AHK-Cu affects proliferation of these cells and prolongation of the anagen (growth) phase.<\/p>\n

Collagen synthesis & tissue matrix<\/h3>\n

Like other copper peptides, AHK-Cu is studied in relation to type I and type III collagen synthesis in dermal fibroblast cultures. The copper ion acts as a cofactor for enzymes such as lysyl oxidase, which are relevant to extracellular matrix cross-linking.<\/p>\n

Angiogenic processes<\/h3>\n

AHK-Cu is studied in relation to new blood vessel formation (angiogenesis). Model studies examine its potential influence on expression of vascular endothelial growth factor (VEGF), which modulates the blood supply to tissues such as skin and hair follicles.<\/p>\n

Oxidative stress & antioxidant enzymes<\/h3>\n

Through its copper binding, AHK-Cu is studied as a modulator of copper-dependent enzymes such as superoxide dismutase. This research area examines the peptide\u2019s role in limiting oxidative stress in cellular models.<\/p>\n

Note: the research areas listed relate exclusively to preclinical laboratory research. No effects in humans are claimed.<\/em><\/p>\n

AESTX Systems quality standards<\/h2>\n
    \n
  • Purity \u226599% (HPLC verified)<\/li>\n
  • Identity confirmed by mass spectrometry<\/li>\n
  • Batch-specific Certificate of Analysis (COA)<\/li>\n
  • Lyophilised powder, packaged for laboratory use<\/li>\n<\/ul>\n

    Laboratory use & handling (research purposes)<\/h2>\n

    AHK-Cu is supplied as lyophilised powder and is not ready to use. For research purposes, it is usually reconstituted with bacteriostatic water. Before reconstitution, store in a cool place protected from light; after reconstitution, refrigerate. Handling is restricted to trained laboratory personnel.<\/p>\n

    \n

    Buy AHK-Cu from AESTX Systems<\/h2>\n

    AHK-Cu<\/strong> complements our copper peptide range as the hair-focused counterpart to GHK-Cu<\/strong>. For laboratories focused on follicle biology, AHK-Cu offers a clearly defined research profile with consistently high specifications.<\/p>\n

    Why choose AHK-Cu from AESTX Systems?<\/h3>\n
      \n
    • Purity \u226599%<\/strong> with a batch-specific Certificate of Analysis<\/li>\n
    • Targeted research profile<\/strong> in hair follicles & the dermal papilla<\/li>\n
    • Consistent specifications<\/strong> across all batches<\/li>\n
    • Discreet shipping<\/strong> and packaging suitable for laboratory use<\/li>\n<\/ul>\n

      AHK-Cu in follicular research<\/h3>\n

      AHK-Cu has primarily been described in hair research, whereas GHK-Cu has a broader focus. Its synthetic origin enables reproducible specifications, which are advantageous for comparative in vitro studies in dermal papilla cells.<\/p>\n

      Research into regenerative mechanisms<\/h3>\n

      The combination of a small tripeptide structure and stable copper complexation makes AHK-Cu an interesting tool for investigating copper-dependent signalling and enzyme pathways in tissue models.<\/p>\n

      Quality, specifications and storage<\/h3>\n

      AHK-Cu is supplied as lyophilised powder with a purity of \u226599% and should be stored in a cool place protected from light.<\/strong><\/p>\n

      Frequently asked questions about buying AHK-Cu<\/h3>\n

      How does AHK-Cu differ from GHK-Cu?<\/strong>
      AHK-Cu uses alanine instead of glycine at the first position and is primarily used in hair follicle research, while GHK-Cu covers a broader range.<\/p>\n

      In what form is AHK-Cu supplied?<\/strong>
      As lyophilised powder with a purity of \u226599% and a batch-specific Certificate of Analysis.<\/p>\n

      Is AHK-Cu ready to use?<\/strong>
      No. AHK-Cu is intended exclusively for laboratory research and must be properly reconstituted before use.<\/p>\n

      Research peptide \u2014 exclusively for laboratory research. Not intended for human consumption or therapeutic use.<\/strong><\/em><\/p>","protected":false},"excerpt":{"rendered":"

      AHK-Cu (Kupfer-Tripeptid-3) ist ein synthetisches Tripeptid aus der Sequenz Alanyl-L-Histidyl-L-Lysin, das ein Kupferion (Cu\u00b2\u207a) in hoher Affinit\u00e4t komplexiert. AHK-Cu ist ein naher Verwandter des nat\u00fcrlich vorkommenden GHK-Cu und unterscheidet sich strukturell lediglich durch den Austausch von Glycin gegen Alanin an der ersten Position. Diese kleine \u00c4nderung verschiebt das Forschungsprofil deutlich in Richtung Haarfollikel-Biologie und macht […]<\/p>\n","protected":false},"featured_media":4208,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[26,109,24],"product_tag":[],"class_list":["post-4146","product","type-product","status-publish","has-post-thumbnail","product_cat-99-purity","product_cat-aesthetik-mehr","product_cat-peptide","first","instock","shipping-taxable","purchasable","product-type-variable"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product\/4146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/comments?post=4146"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/media\/4208"}],"wp:attachment":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/media?parent=4146"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product_brand?post=4146"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product_cat?post=4146"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product_tag?post=4146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}