{"id":429,"date":"2026-04-10T16:48:19","date_gmt":"2026-04-10T16:48:19","guid":{"rendered":"https:\/\/firebrick-hamster-619463.hostingersite.com\/?post_type=product&#038;p=429"},"modified":"2026-07-23T21:50:52","modified_gmt":"2026-07-23T21:50:52","slug":"mots-c","status":"publish","type":"product","link":"https:\/\/aestx-systems.com\/en\/product\/mots-c\/","title":{"rendered":"MOTS-c"},"content":{"rendered":"<p>Looking to <strong>buy MOTS-c<\/strong>? AESTX Systems supplies the peptide <strong>MOTS-c<\/strong> with \u226599% purity (HPLC) and a batch-specific COA \u2014 exclusively for research purposes.<\/p>\n<p><strong>MOTS-c<\/strong> (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrially encoded peptide of 16 amino acids, transcribed from the small ribosomal RNA gene (12S rRNA) of mitochondrial DNA. MOTS-c is considered the first known <strong>mitochondrial hormesis factor<\/strong> and is extensively studied in metabolism and longevity research.<\/p>\n<h2>Research areas for MOTS-c (mitochondrial hormesis factor)<\/h2>\n<h3>Mitochondrial communication &amp; mitokine research<\/h3>\n<p>MOTS-c is described as a mitokine produced in mitochondria that can translocate to the nucleus, where it activates AMPK signalling pathways and the AICAR metabolic pathway.<\/p>\n<h3>Metabolism &amp; insulin sensitivity research<\/h3>\n<p>In preclinical models, MOTS-c is studied in relation to glucose homeostasis, insulin sensitivity and AMPK activation in skeletal muscle and adipose cell cultures.<\/p>\n<h3>Longevity &amp; anti-ageing research<\/h3>\n<p>In research models of cellular ageing, MOTS-c is described in relation to regulation of senescence markers and age-related tissue deterioration.<\/p>\n<h3>Physical performance \u2014 preclinical research<\/h3>\n<p>Animal studies investigate MOTS-c in relation to the oxidative capacity of skeletal muscles and physical endurance.<\/p>\n<p><em>Anecdotal note: reports from the research community describe strong interest in longevity and metabolic research questions. Such reports are not scientifically substantiated, do not constitute promises of efficacy and relate exclusively to research.<\/em><\/p>\n<h2>AESTX Systems quality standards<\/h2>\n<ul>\n<li>Purity \u226599% \u2014 verified by HPLC<\/li>\n<li>Certificate of analysis (COA) available<\/li>\n<li>Form: lyophilised powder \u2014 laboratory quality<\/li>\n<li>Fast &amp; discreet shipping from Germany (Germany &amp; EU)<\/li>\n<\/ul>\n<h2>Laboratory use &amp; handling (research purposes)<\/h2>\n<p>Lyophilised powder for reconstitution under laboratory conditions. For use by qualified personnel only.<\/p>\n<hr>\n<h2>Buy MOTS-c from AESTX Systems<\/h2>\n<p>Looking to <strong>buy MOTS-c<\/strong>? AESTX Systems supplies the peptide <strong>MOTS-c<\/strong> as a lab-tested reference material with an HPLC-confirmed purity of <strong>\u2265 99 %<\/strong>. Every batch is analytically tested for purity and identity and supplied with a batch-specific certificate of analysis (COA). The material is intended exclusively for research and laboratory use.<\/p>\n<h3>MOTS-c in metabolism research<\/h3>\n<p>MOTS-c is a mitochondrially encoded peptide studied in relation to regulation of cellular energy metabolism and metabolic homeostasis. In vitro models examine its role in AMPK activation and the insulin sensitivity of cell cultures.<\/p>\n<h3>Research into mitochondrial signalling<\/h3>\n<p>Scientific studies describe MOTS-c as a mitochondrial signalling peptide that responds to metabolic stress. As a high-purity reference substance, it is used to characterise mitochondrial signalling pathways under standardised laboratory conditions.<\/p>\n<h3>Why choose MOTS-c from AESTX Systems?<\/h3>\n<ul>\n<li><strong>\u226599% purity<\/strong> \u2014 every batch analysed by HPLC for purity and identity<\/li>\n<li><strong>Batch-specific COA<\/strong> \u2014 complete certificate of analysis with every delivery<\/li>\n<li><strong>Shipping from Germany<\/strong> \u2014 fast, discreet delivery within Germany and to Austria<\/li>\n<li><strong>Research Use Only<\/strong> \u2014 appropriate declaration and documentation as a reference substance<\/li>\n<\/ul>\n<h3>Quality, specifications and storage<\/h3>\n<p>Research and educational institutions looking to obtain <strong>MOTS-c in Germany<\/strong> as a reference material receive consistently documented quality from AESTX Systems. Purity of \u226599% is determined using high-performance liquid chromatography (HPLC); identity and molecular weight are analytically confirmed. In research practice, the lyophilised material is described as being stored in a cool, dry place protected from light; after reconstitution, it is refrigerated. All purity, batch and specification information can be traced through the accompanying COA. Names used in scientific contexts include <strong>Mitochondrial ORF of the 12S rRNA-c<\/strong>.<\/p>\n<h3>Frequently asked questions about buying MOTS-c<\/h3>\n<p><strong>What is the purity of MOTS-c from AESTX Systems?<\/strong><br \/>The MOTS-c offered has an HPLC-confirmed purity of \u226599% and is supplied with a batch-specific Certificate of Analysis.<\/p>\n<p><strong>Are products shipped from Germany?<\/strong><br \/>Yes. MOTS-c is shipped quickly and discreetly from Germany to destinations within Germany and Austria.<\/p>\n<p><strong>Who is the product intended for?<\/strong><br \/>MOTS-c is intended exclusively for research and laboratory use by qualified research and educational institutions and appropriately knowledgeable individuals.<\/p>\n<p><em><strong>Research disclaimer:<\/strong> This product is intended exclusively for research and laboratory use (in vitro). It is not intended for human or animal use and is not a medicine, food or cosmetic. It is not intended to diagnose, treat, cure or prevent disease and does not replace medical advice. Purchase is restricted to qualified research and educational institutions and appropriately knowledgeable individuals.<\/em><\/p>\n<p class=\"ax-crosslink-pen\">\ud83d\udc89 <strong>Also available as an injection pen:<\/strong> <a href=\"https:\/\/aestx-systems.com\/en\/product\/mots-c-pen\/\">MOTS-c Pen \u2014 prefilled, no reconstitution required<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p><strong>MOTS-c<\/strong> \u2013 mitochondrial kodierter Hormese-Faktor f\u00fcr Metabolismus-, AMPK- &amp; Longevity-Forschung. HPLC-gepr\u00fcfte Reinheit \u2265 99 %, mit COA. Nur f\u00fcr Forschungszwecke \u2013 Versand aus Deutschland.<\/p>","protected":false},"featured_media":438,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[26,106,24],"product_tag":[],"class_list":["post-429","product","type-product","status-publish","has-post-thumbnail","product_cat-99-purity","product_cat-energie-zellschutz","product_cat-peptide","first","instock","sale","shipping-taxable","purchasable","product-type-variable","has-default-attributes"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product\/429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/comments?post=429"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/media\/438"}],"wp:attachment":[{"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/media?parent=429"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product_brand?post=429"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product_cat?post=429"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/aestx-systems.com\/en\/wp-json\/wp\/v2\/product_tag?post=429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}