MOTS-c

Looking to buy MOTS-c? AESTX Systems supplies the peptide MOTS-c with ≥99% purity (HPLC) and a batch-specific COA — exclusively for research purposes.

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrially encoded peptide of 16 amino acids, transcribed from the small ribosomal RNA gene (12S rRNA) of mitochondrial DNA. MOTS-c is considered the first known mitochondrial hormesis factor and is extensively studied in metabolism and longevity research.

Research areas for MOTS-c (mitochondrial hormesis factor)

Mitochondrial communication & mitokine research

MOTS-c is described as a mitokine produced in mitochondria that can translocate to the nucleus, where it activates AMPK signalling pathways and the AICAR metabolic pathway.

Metabolism & insulin sensitivity research

In preclinical models, MOTS-c is studied in relation to glucose homeostasis, insulin sensitivity and AMPK activation in skeletal muscle and adipose cell cultures.

Longevity & anti-ageing research

In research models of cellular ageing, MOTS-c is described in relation to regulation of senescence markers and age-related tissue deterioration.

Physical performance — preclinical research

Animal studies investigate MOTS-c in relation to the oxidative capacity of skeletal muscles and physical endurance.

Anecdotal note: reports from the research community describe strong interest in longevity and metabolic research questions. Such reports are not scientifically substantiated, do not constitute promises of efficacy and relate exclusively to research.

AESTX Systems quality standards

• Purity ≥99% — verified by HPLC
• Certificate of analysis (COA) available
• Form: lyophilised powder — laboratory quality
• Fast & discreet shipping from Germany (Germany & EU)

Laboratory use & handling (research purposes)

Lyophilised powder for reconstitution under laboratory conditions. For use by qualified personnel only.

Buy MOTS-c from AESTX Systems

Looking to buy MOTS-c? AESTX Systems supplies the peptide MOTS-c as a lab-tested reference material with an HPLC-confirmed purity of ≥ 99 %. Every batch is analytically tested for purity and identity and supplied with a batch-specific certificate of analysis (COA). The material is intended exclusively for research and laboratory use.

MOTS-c in metabolism research

MOTS-c is a mitochondrially encoded peptide studied in relation to regulation of cellular energy metabolism and metabolic homeostasis. In vitro models examine its role in AMPK activation and the insulin sensitivity of cell cultures.

Research into mitochondrial signalling

Scientific studies describe MOTS-c as a mitochondrial signalling peptide that responds to metabolic stress. As a high-purity reference substance, it is used to characterise mitochondrial signalling pathways under standardised laboratory conditions.

Why choose MOTS-c from AESTX Systems?

• ≥99% purity — every batch analysed by HPLC for purity and identity
• Batch-specific COA — complete certificate of analysis with every delivery
• Shipping from Germany — fast, discreet delivery within Germany and to Austria
• Research Use Only — appropriate declaration and documentation as a reference substance

Quality, specifications and storage

Research and educational institutions looking to obtain MOTS-c in Germany as a reference material receive consistently documented quality from AESTX Systems. Purity of ≥99% is determined using high-performance liquid chromatography (HPLC); identity and molecular weight are analytically confirmed. In research practice, the lyophilised material is described as being stored in a cool, dry place protected from light; after reconstitution, it is refrigerated. All purity, batch and specification information can be traced through the accompanying COA. Names used in scientific contexts include Mitochondrial ORF of the 12S rRNA-c.

Frequently asked questions about buying MOTS-c

What is the purity of MOTS-c from AESTX Systems?
The MOTS-c offered has an HPLC-confirmed purity of ≥99% and is supplied with a batch-specific Certificate of Analysis.

Are products shipped from Germany?
Yes. MOTS-c is shipped quickly and discreetly from Germany to destinations within Germany and Austria.

Who is the product intended for?
MOTS-c is intended exclusively for research and laboratory use by qualified research and educational institutions and appropriately knowledgeable individuals.

Research disclaimer: This product is intended exclusively for research and laboratory use (in vitro). It is not intended for human or animal use and is not a medicine, food or cosmetic. It is not intended to diagnose, treat, cure or prevent disease and does not replace medical advice. Purchase is restricted to qualified research and educational institutions and appropriately knowledgeable individuals.

💉 Also available as an injection pen: MOTS-c Pen — prefilled, no reconstitution required.